Dr. Oleksandr Pokholenko


School of Materials Science and Engineering
Nanyang Technological University
Office: N3-01C-10
50 Nanyang Avenue
Singapore 639798

email: opokholenko@ntu.edu.sg


Oleksandr Pokholenko got his Ph.D from Taras Shevchenko University of Kyiv, Ukraine in 2003, where he stayed lateron as an associate researcher till 2005 concentrated on chemistry of heterocyclic compounds as well as cycloaddition reactions. Later he moved to Life Chemicals company, located also in Kyiv, where he applied his skills towards drug discovery projects and molecular modeling. In 2010-2011 years he stayed at ChemBioMed group of Prof. Philippe Barthélémy at ARNA Lab INSERM U869 unit at University of Bordeaux, France, where he got interested in studying structural features of biomacromolecules and their chemical modifications as well as designing drug delivery systems. Since 2014 he joined the research team of Prof. Terry W. J. Steele at Materials Science and Engineering School of Nanyang Technological University with focus on biophysical chemistry of biomacromolecules, their chemical modifications, especially those, friendly to in vivo conditions as well as biomaterials.

Research Interests

Physical chemistry of biomacromolecules. Chemical modifications of biomacromolecules, using them in materials science and nanotechnology.


[7]O. Pokholenko et al., "Lipid oligonucleotide conjugates as responsive nanomaterials for drug delivery", Journal of Materials Chemistry B, vol. 1, no. 39, sep 2013, pp. 5329-5334. [doi]
[6]A. Aimé et al., "Quantum Dot Lipid Oligonucleotide Bioconjugates: Toward a New Anti-MicroRNA Nanoplatform", Bioconjugate Chemistry, vol. 24, no. 8, aug 2013, pp. 1345-1355. [doi]
[5]Z. V. Voitenko et al., "Benzo[f]isoindole derivatives from cycloaddition reaction of 2,4-dimethylpyrimido[2,1-a]isoindole and maleimides", Comptes Rendus Chimie, vol. 9, no. 11–12, nov 2006, pp. 1482-1487. [doi]
[4]A. A. Pokholenko, Z. V. Voitenko and V. A. Kovtunenko, "Pyrido- and pyrimidoisoindoles: methods of synthesis and properties", Russian Chemical Reviews, vol. 73, no. 8, aug 2004, pp. 771. [doi]
[3]Z. V. Voitenko et al., "Cycloaddition in Condensed Isoindoles. 2. Method for Obtaining New Derivatives of 2-Phenylpyridine", Chemistry of Heterocyclic Compounds, vol. 38, no. 2, feb 2002, pp. 190-196. [doi]
[2]N. S. Allen et al., "Novel oligomeric amines as co-synergists for the photosensitised crosslinking of a triacrylate resin", Polymer Degradation and Stability, vol. 75, no. 2, 2002, pp. 229-236. [doi]
[1]Z. V. Voitenko et al., "Structure of the Cycloaddition Products of Pyrido[2,1-a]isoindole with Maleimide Derivatives: X-ray Diffraction Analysis and 1H NMR Variable-Temperature Spectra", European Journal of Organic Chemistry, vol. 2001, no. 7, 2001, pp. 1401–1405. [doi]